Novartis |
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Clinical Trials: Good Clinical Practice (CourseraSpecs) https://www.coursera.org/specializations/clinical-trials-good-clinical-practice Offered by Novartis. GCP Principles for Ethical Clinical Trials |
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Drug Hunting: The Science of Making New Medicines (CourseraSpecs) https://www.coursera.org/specializations/drug-hunting-discovery-and-development Offered by Novartis. Understanding Drug Discovery and Development |
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Fundamentals of Good Clinical Practice: Prep and Personnel (Coursera) https://www.coursera.org/learn/fundamentals-of-gcp-prep-staffing Welcome to 'Fundamentals of Good Clinical Practice: Prep and Personnel'! This course is designed to introduce you to preparing for a clinical trial. This is Course Two in the Clinical Trial Teams series - the first course 'Introduction to Good Clinical Practice' provides background on what clinical trials are as well as the basic principles and practices of GCP. If you are new to the world of clinical research, we suggest starting your journey with Course One. In Course Two, we turn our atten |
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Fundamentals of Good Clinical Practice: Recruitment & Trial (Coursera) https://www.coursera.org/learn/gcp-recruitment Welcome to 'Fundamentals of Good Clinical Practice: Recruitment and Trial'! This is the third course in the Clinical Trial GCP series. It is designed to introduce you to the processes, procedures and documentation needed prior, during and after a clinical trial according to Good Clinical Practice (GCP). In Courses One and Two, we explored the foundations of clinical research, including the preparations and documentation needed to begin a trial as well as the role of the investigator, site st |
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Introduction to Drug Hunting (Coursera) https://www.coursera.org/learn/introduction-to-drug-hunting This course introduces and summarizes the different steps of preclinical drug discovery, wrapping up with a brief description of the subsequent clinical trials and the importance of competitive intelligence in project strategy. It provides a high-level overview for those interested in a more general understanding of the topic and forms the foundation for a more in-depth exploration of topics covered in other courses in this series. Target audience: This course is suitable for life scientists, |
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Introduction to Good Clinical Practice (Coursera) https://www.coursera.org/learn/good-clinical-practice-novartis Welcome to 'Introduction to Good Clinical Practice'! This course is designed to introduce you to the basic principles and practices of Good Clinical Practice (GCP), which are essential for conducting clinical trials and ensuring the safety and well-being of human subjects. Whether you are new to the field or seeking to refresh your knowledge, this course and its sequel courses covering the fundamentals of Good Clinical Practice will equip you with the necessary skills and understanding to begin |
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Lead Selection & Optimization (Coursera) https://www.coursera.org/learn/lead-selection-optimization This course covers the stages of drug discovery in which promising compounds (leads) are identified, their optimal and suboptimal characteristics determined, and the suboptimal characteristics optimized to create a candidate suitable for the clinic. The course is built around a case study on the discovery of an antimalarial therapy. Assays useful for screening new compounds are outlined, examples of selection criteria for leads are discussed - such as potency, efficacy, and pharmacokinetics - |
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https://www.coursera.org/learn/pharmacokinetics This course begins with a review of routes of administration, ADME (absorption, distribution, metabolism, & excretion), and the use of in vivo drug concentration-time data to determine key pharmacokinetic parameters, like volume of distribution, half-life and clearance. The course then emphasizes in vitro assays that allow rapid prediction of ADME and PK properties for evaluation of new compounds. The later stages of the course focus on how drug discovery teams study this PK/PD relationship, a |
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https://www.coursera.org/learn/pre-formulation In this course we will focus on how active compounds are developed into a formulation suitable for dosing in animal studies and early human clinical trials. Factors such as the route of administration, enhancing the solubility of the drug substance, the crystalline form of the drug substance, drug substance vs. drug product, storage requirements, and how special requirements of the patient population play a role in the design of an ideal formulation will be covered. Finally, some of the differ |
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https://www.coursera.org/learn/preclinical-safety Patient safety is of paramount importance for any drug discovery program. This course looks at some of the lessons learned which have influenced how promising molecules are currently evaluated for safety risks. In vitro and in vivo toxicology and safety studies are discussed, why they are performed, and how the data they provide guide a safety risk assessment, including determining a therapeutic index or safety window for a drug. Finally, the course will look at how safety data guide human do |
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Targets, Assays & Screening (Coursera) https://www.coursera.org/learn/targets-assays-screening This course focuses on the early stages of drug discovery and the identification of promising compounds with which to begin the hunt for a novel drug. Different types of assays and methods are reviewed that are used to screen libraries of molecules in the preliminary search for compounds with activity. Methods are discussed for validating that active molecules are indeed engaging a target associated with a predicted therapeutic benefit. Target audience: This course is suitable for life scien |