Pharmacokinetics

Novartis via Coursera

Go to Course: https://www.coursera.org/learn/pharmacokinetics

Syllabus

Pharmacokinetics, part 1

Welcome, by the end of the course students will be able to: Summarize the key concepts of pharmacokinetics (PK), ADME (Absorption, Distribution, Metabolism, and Excretion), volume of distribution, half-life and clearance. Differentiate between different routes of drug administration and their impact on PK parameters. Define and describe the influence of transporters, plasma protein binding (PPB) and drug-drug interactions (DDIs) on the PK of a drug molecule. Explain how PK/PD relationships are derived and their importance for defining the anticipated human dose.

Pharmacokinetics, part 2

Pharmacokinetics, part 3

Overview

This course begins with a review of routes of administration, ADME (absorption, distribution, metabolism, & excretion), and the use of in vivo drug concentration-time data to determine key pharmacokinetic parameters, like volume of distribution, half-life and clearance.  The course then emphasizes in vitro assays that allow rapid prediction of ADME and PK properties for evaluation of new compounds.  The later stages of the course focus on how drug discovery teams study this PK/PD relationship, a

Skills

Reviews

Amazing to-the-point course content, great citations to key articles and questions which are very helpful for permenance. I'm pleased as a medical doctor in drug research. Thanks for this course!

Amazing course for people intending to pursue higher studies in the field of pharmacology

I enjoyed the entire specialization thanks to great bit sized lectures, additional readings, videos and exploratory exercises.

Excellent at offering concepts of Pharmacokinetics

Overall comprehensive basic content, clearly presented. Feedback on quizzes and assignments needs to be clearer and more informative in some cases.