Overview

RNA is a polymer of ribonucleotides held together by 3 ,5 -phosphodiester bridges.Although RNA has certain similarities with DNA structure ,they have several specific differences.1.Pentose The sugar :in RNA is ribose in contrast to deoxyribose in DNA. 2.pyrimidine: RNA contains the pyrimidine uracil in place of thymine 3.Single strand: RNA is usually a single stranded polynucleotide. How ever, this strand may fold at certain places to give a double stranded structure, if complementary base pairs are in close proximity.4.chargaff"srule - not obeyed: Due to the single- stranded nature, there is no specific relation between purine and pyrimidine contents.Thus the guanine contents is not equal to cytosine(as is the case in DNA)5.Susceptability to alkali hydrolysis: Alkali can hydrolyze RNA to 2,3-cyclic diesters.This is possible due to the presence of a hydroxyl group at 2 position.DNA cannot be subjected to alkali hydrolysis due to lack of this group.6.Orcinol color reaction:RNAs can be histologically identified by orcinol color reaction due to the presence of ribose.Types of RNA: mRNA, rRNA and tRNARNA or ribonucleic acid is a polymer of nucleotides that is made up of a ribose sugar, a phosphate, and bases such as adenine, guanine, cytosine, and uracil. It plays a crucial role in gene expression by acting as the intermediate between the genetic information encoded by DNA and protein RNA has a structure very similar to that of DNA. The key difference in RNA structure is that the ribose sugar in RNA possesses a hydroxyl (-OH) group that is absent in DNA.and much more you can find in session presentations.

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