Molecular biology

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Overview

Introduction to the course Provides information onBrief introduction on TutorBenefits from the courseTopics/Structure of the courseWho can enroll to the course UNIT 1: Replication Central Dogma of biologyReplication of DNASemiconservative replication Complimentary base pairingSupercoil and DNA topoisomeraseReplication forkDNA synthesis catalysed by DNA Polymerase DNA Damage and Repair Nucleotide Excision Repair Base Excision Repair Mismatch Repair system UNIT 2: Transcription Central Dogma of Life what is Transcription Mechanism Of Transcription In Prokaryotes Initiation elongation Termination In Eukaryotes Initiation is initiated with help of promotor regionTAAT Box and Pribnow BoxElongation Enhancers and Silencers Termination Post Transcriptional Modification Addition of Cap and Poly A tail Splicing Of mRNA mRNA Editing Inhibitors of Transcription Reverse Transcriptase and RNA Degradation.UNIT 3: Translation Genetic Code Features Of Genetic Code Codon - Anticodon Pairing wobble HypothesisLink Between Amino Acid And Nucleic Acid Translation In Prokaryotes Initiation Elongation Termination How much Energy is consumed during the Process Translation in Eukaryotes Initiation with Pre Initiation complex Association of Ribosomal Subunit Elongation Termination using Termination Codons Release Factors Post Translational Modification Trimming Structural Reorganisation Modification at N and C Terminal Ends Covalent Modification How much Of energy is consumed during the process of Translation Unit 4: Regulation of Gene Expression Enhancers and silencers House keeping and invisible genes One cistron -one subunit concept DNA organisation and Gene expression Covalent Modification of Histones control Gene expression Regulation of Gene Expression in Prokaryotes: Lac operon structure of Lac Operon Tryptophan regulation in Eukaryotes Structure of Tryptophan Operon with structural gene

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