The Science of Stem Cells

Go to Course: https://www.coursera.org/learn/stem-cells

Introduction

**Course Review: The Science of Stem Cells on Coursera** If you’re fascinated by the frontiers of medical science and technology, “The Science of Stem Cells” on Coursera is an excellent course that merits your attention. This five-part online course offers a comprehensive introduction to the world of stem cells, exploring their history, biology, potential therapies, and the ethical considerations surrounding their use. ### Overview The course is designed for anyone interested in understanding the promising possibilities that stem cells hold for the treatment of various medical conditions. Whether you are a student, a healthcare professional, or just a curious individual, this course opens the door to groundbreaking research and therapeutic innovations that are shaping the future of medicine. ### Course Structure **1. Introduction to Stem Cells** The opening module provides an extensive overview of what stem cells are, tracing their history and significance. With contributions from biologist Julia Zichello of the American Museum of Natural History, the session delves into the remarkable presence of stem cells across the tree of life, laying a solid foundation for the rest of the course. **2. How Do Stem Cells Work?** In the second week, you’re introduced to advanced concepts from Dr. Esteban Mazzoni at New York University. This segment explores techniques that scientists use to manipulate stem cells, including differentiation into specific cell types. Additionally, cutting-edge topics such as mitochondrial replacement therapy and the ethical ramifications of cloning are covered, giving learners insight into the science behind organ transplantation. **3. Using Stem Cells to Study Disease** Moving beyond the basics, this module addresses how stem cells can be utilized to model diseases. Dr. Andrew Sproul from Columbia University expertly walks you through the ways in which cultured cells can reveal potential cures for diseases like Alzheimer’s and diabetes, highlighting the critical role stem cells play in drug discovery and disease understanding. **4. Using Stem Cells to Treat Disease** The course then shifts focus to practical applications, discussing how stem cells can be harnessed in therapies. Dr. Sally Temple, a pioneer in neural stem cell research, offers fascinating insights into treating age-related macular degeneration using adult stem cells. This section is particularly compelling for those curious about real-world applications and patient outcomes. **5. The Bioethics of Stem Cell Research and Therapy** No discussion of stem cells would be complete without addressing the ethical dilemmas they present. In the final module, a panel of bioethics experts navigates the controversies surrounding human embryonic stem cells. This segment encourages learners not only to absorb knowledge but also to engage in meaningful discussions about the future implications of reproductive technology and stem cell research. ### Key Takeaways - **Expert Insights**: Featuring contributions from recognized scientists and researchers, the course provides learners with robust knowledge and expertise. - **Engagement with Ethical Perspectives**: Understanding the ethical implications is crucial in the field of stem cell research. This course emphasizes the importance of addressing these challenges. - **Real-World Applications**: The course does not merely dwell on theory; it translates scientific findings into potential life-changing therapies. ### Recommendation “The Science of Stem Cells” is highly recommended for those who want to delve into one of the most exciting areas of biology and medicine. The structure of the course, combined with expert insights and ethical discussions, makes it an enriching experience for learners at various levels of understanding. Whether you're a medical professional looking to broaden your knowledge, a student aiming for a career in biotech, or simply a curious individual interested in the future of healing, this course will equip you with valuable insights and a deeper appreciation for the potential of stem cells. Enroll now and take the first step toward understanding the promise and challenges of this remarkable field!

Syllabus

Introduction to Stem Cells

Welcome to The Science of Stem Cells! You will begin with a basic overview of stem cells--what they are, the history of stem cell research, and the potential for stem cell therapies. You will also learn from AMNH biologist Julia Zichello that stem cells are found throughout the tree of life.

This week, New York University’s Dr. Esteban Mazzoni will discuss how scientists can coax stem cells to differentiate into particular cell types. Dr. Mazzoni will also talk about new stem cell-assisted technologies such as mitochondrial replacement therapy and generating chimeras for organ transplantation. You will also get some background information on the science and ethics of cloning.

We have covered the process by which scientists can differentiate cells in a culture dish. Now you will look at how scientists can use these cell to model diseases in a culture dish. Dr. Andrew Sproul from Columbia University explains how cultured cells can be used to understand the cause of diseases and to look for drugs that will potentially cure them. His research is on Alzheimer’s disease. You will also explore how how stem cells have the potential to help with the study of diabetes.

In addition to the great potential of stem cells to be used in the study of disease, stem cells can also be used to actually treat disease. Neural stem cell pioneer Dr. Sally Temple will explain the potential for using stem cells in our own bodies (adult stem cells) to treat age-related macular degeneration, an increasingly common and debilitating disease. Dr. Temple will also give you some tools for evaluating potential stem cell treatments.

To complete the course, a panel of bioethics experts will discuss some of the controversies surrounding human embryonic stem cells and the legal, policy, and ethical challenges associated with the use of stem cells in basic and clinical research. You will have an opportunity to discuss and ask questions about the future of reproductive technology and stem cell research.