Introduction to Molecular Spectroscopy

University of Manchester via Coursera

Go to Course: https://www.coursera.org/learn/spectroscopy

Introduction

### Course Review: Introduction to Molecular Spectroscopy If you’re passionate about chemistry or biochemistry and eager to deepen your understanding of molecular structures, the "Introduction to Molecular Spectroscopy" course on Coursera is an excellent choice. This engaging course covers three fundamental spectroscopic methods—UV/Visible, Infra-red (IR), and Nuclear Magnetic Resonance (NMR)—that are pivotal in analyzing the molecular and electronic structure of atoms and molecules. #### Overview The course is structured to offer learners a comprehensive introduction to the principles and applications of molecular spectroscopy. It utilizes dynamic screencast presentations that present the material in an interactive format, complemented by formative quizzes. These quizzes serve as valuable checkpoints to enhance understanding and retention of the key concepts presented. Further, the course is rich with exercises designed to help you master each topic thoroughly. #### Syllabus Breakdown **Week 1: Ultraviolet and Visible Spectroscopy** In the first week, students are introduced to the fundamental concepts of UV/Visible spectroscopy. The module begins with a discussion on the electromagnetic spectrum, explaining how electronic transitions occur through the absorption of UV/Vis radiation. Learners will engage with content that explains the relationship between wavelength, intensity of bands, and the color of various compounds. Importantly, students will perform spectral analysis by running their own UV/Visible spectra and will have access to laboratory demonstrations to visualize the practical application of the theory. The week culminates with a laboratory quiz that solidifies the learning objectives. **Week 2: Infrared Spectroscopy** The second week delves into the intricacies of infrared (IR) spectroscopy. It starts with theoretical foundations using the simple harmonic oscillator model, paving the way for understanding transitions between vibrational energy levels. What makes this module particularly engaging is the discussion on how to analyze complex molecules through group frequencies and vibrational modes. As in the first week, students will have practical opportunities to obtain IR spectra, and they will also complete a quiz to assess their comprehension of the week's topics. **Week 3: Nuclear Magnetic Resonance (NMR) Spectroscopy** In the final week, the course focuses on Nuclear Magnetic Resonance (NMR) spectroscopy, an essential tool for molecular structure determination. This module introduces students to the creation of energy levels for magnetic nuclei and how transitions occur in the radiofrequency region. Learners will understand the significance of chemical shifts and the fine structure of bands resulting from spin-spin coupling. Real-world examples will be provided to help you grasp the applications of NMR in structural analysis. As with previous modules, a quiz will finalize the week, reinforcing the knowledge acquired. **Final Assessment** The course adeptly evaluates your knowledge through a comprehensive final assessment, ensuring that you have a solid understanding of the material covered. #### Conclusion & Recommendation Overall, "Introduction to Molecular Spectroscopy" is an enriching and essential course for anyone interested in the chemical sciences. The blend of engaging video presentations, practical exercises, and quizzes provides an effective learning environment. The hands-on aspects of the course—particularly the laboratory demonstrations and the opportunity to analyze your own spectra—directly bridge theory and practice, making it both informative and applicable. Whether you're a student pursuing a degree in chemistry or a professional looking to refresh your knowledge, I highly recommend this course. It offers a solid foundation in molecular spectroscopy and equips you with the theoretical and practical skills necessary for further exploration in the field. Enroll today to unlock the mysteries of molecular analysis through spectroscopy!

Syllabus

Ultraviolet and Visible Spectroscopy

In this first week we introduce the electromagnetic spectrum and the origin of transitions giving rise to ultraviolet and visible (UV/Vis) spectra. You will learn that electronic transitions are caused by absorption of radiation in the UV/Vis region of the electromagnetic spectrum. The reason for the wavelength and intensity of bands will be described and the colour origin of certain compounds will be discussed. You will also be shown how UV/Vis spectroscopy is performed and you will be able to run and analyse your own spectra. As the final activity in this module you are given a link to view how to obtain a UV/Visible spectrum in the laboratory. Good luck, try and participate in the discussion forums to enhance your learning and don't forget to complete the end of week laboratory quiz which contributes to your final mark.

Infrared Spectroscopy

In this module we introduce the theory underpinning infrared (IR) spectroscopy and show examples of analysis using the technique. Transitions between the vibrational energy levels of molecules occurs in the infrared region of the electromagnetic spectrum. We start with the theory underlying vibration using the simple harmonic oscillator model. Analysis of more complex molecules is introduced using group frequencies and number of vibrational modes. You will also be shown how to obtain an infrared spectrum and will have an opportunity to run your own spectrum. At the end of this module you are given a link to view how to obtain an infra red spectrum in the laboratory. Don't forget to complete the end of week laboratory quiz which contributes to your final mark for this course.

Nuclear Magnetic Resonance (NMR) Spectroscopy

This week we concentrate on Nuclear Magnetic Resonance (NMR) spectroscopy. Here a magnetic field is used to create energy levels for magnetic nuclei present in a molecule. Transition between these energy levels occurs in the radiofrequency region of the electromagnetic spectrum. The positions of the bands in the observed spectrum is dependent on the shielding of the nuclei by the local electronic structure, giving rise to a parameter known as chemical shift. Bands also display fine structure caused by spin-spin coupling with neighbouring nuclei. Examples on the analysis of NMR spectra for structure determination will be given. As the final activity in this module you are given a link to view how to obtain an NMR spectrum in the laboratory. Don't forget to compete this end of week laboratory quiz which contributes to your final mark.

Final Assessment

Overview

The course introduces the three key spectroscopic methods used by chemists and biochemists to analyse the molecular and electronic structure of atoms and molecules. These are UV/Visible , Infra-red (IR) and Nuclear Magnetic Resonance (NMR) spectroscopies. The content is presented using short focussed and interactive screencast presentations accompanied by formative quizzes to probe understanding of the key concepts presented. Numerous exercises are provided to facilitate mastery of each topic. A

Skills

Reviews

Practical and worthwhile. Supplementary short videos that give a brief overview of each technique was helpful for me to get a handle of some of the theoretical concepts.

I learned a lot about the physics behind spectroscopy. The lectures were easy to follow and understand and the notes were detailed. I definitely recommend this course for chemistry-related majors.

Some of the questions had wrong answers in the system and hence the actual marks shown is not reflective of the exam. Please see to it that the system has correct answers.

This course helped me to further understand the principle behinds the 3 main spectroscopic techniques: UV/VIS, IR and NMR which is very beneficial for my future career working in a lab environment.

I would like to thank the instructor Patrick J O'Malley, D.Sc for the very high energetic and interesting online lecture. Really, it enriched my knowledge of Molecular Spectroscopy